The CYBER-TRUST project aims to develop an innovative cyber-threat intelligence gathering, detection, and mitigation platform to tackle the grand challenges of securing the ecosystem of IoT devices. The security problems arising from the flawed design of legacy hardware and embedded devices allow cyber-criminals to easily compromise them and launch large-scale attacks on critical cyber infrastructures. Novel technologies will be developed, based on distributed ledgers and blockchains, to monitor devices’ integrity state and network behavior that will considerably increase the detection and response capabilities against targeted and interdisciplinary cyber-attacks. In the case of alleged malicious activity, tools for collecting and storing forensic evidence on a tamper-proof blockchain structure will be delivered, taking into account the specific needs of law enforcement agencies. Privacy-preserving network monitoring and advanced virtual reality-based visualization techniques will be employed for quickly detecting botnets, DDoS attacks, and other incidents.